2013 Molecular Psychiatry Meeting Schedule
Download a PDF of all three days here
Friday, November 8th
Time | Pacific Room JK | |
---|---|---|
7:50 am | Opening Remarks: William Byerley, UCSF | |
8:00 am | Plenary Session: Sam Barondes Introduction: Rob Malenka, Stanford: Exploring Circuits Underlying Reward And Aversion | |
8:50 am | Break | |
Time | Pacific Room JK | Pacific Room M |
9:00 am |
Gene Expression Analysis Of Psychiatric DisordersPablo Gejman, Chair And Co-chair Dan Rujescu, Co-chair9:00 am: Dan Rujescu, Munich Center For Neurosciences Expression Analysis Of Rat Psychosis Model Identifies Novel Candidate Genes Validated In The Largest Case-control Sample Of Schizophrenia 9:24 am: Danny Weinberger, Lieber Institute Splice Variation And Molecular Mechanisms Of Genetic Association 9:48 am: Karoly Mirnics, Vanderbilt University Neuroimmune Changes In Schizophrenia 10:12 am: Murray Cairns, The University Of Newcastle/New South Wales Analysis Of Micro RNA Expression And Interactions In Neuropsychiatry 10:36 am: Pablo Gejman, University Of Chicago And North Shore University Health System A Mechanistic Approach To The Study Of Gene Expression In A Large Schizophrenia Dataset |
Dopaminergic Neuromodulation Of Limbic SystemsMark Van Zastrow, Chair And Vikaas Sohal, Co-chair9:00 am: Patricio O’Donnell, Pfizer Are D1 And D2 Receptors Viable Targets In Schizophrenia? 9:24 am: Linda Wilbrecht, UC Berkeley Brief Stimulation Of Subpopulations Of Striatal Neurons Produces Dissociable Effects On Action Selection And Evaluation 9:48 am: Jennifer Whistler, UCSF/Gallo Center Dopamine Receptor Trafficking Modulates Neuronal And Behavioral Plasticity 10:12 am: Vikaas Sohal, UCSF D2R Modulation Of Prefrontal Microcircuits 10:36 am: Mark Van Zastrow, UCSF D1R Signaling And Membrane Traffic In Medium Spiny Neurons |
11:00 am | Discussion | Discussion |
11:30 am | Lunch | |
1:00 pm |
Imaging Studies For SchizophreniaSteven Potkin, Chair And Judy Ford, Co-chair1:00 pm: Judith Ford, UCSF Visual Hallucinations Are Associated With Visual Cortex Hyperconnectivity To Amygdala And Hippocampus 1:30 pm: Theo Van Erp, UC Irvine Structural Abnormalities In Schizophrenia 2:00 pm: James Waltz, University Of Maryland Reinforcement Learning Deficits In Schizophrenia: Contributions From Multiple Neural Networks 2:30 pm: J. Daniel Ragland, UC Davis Functional And Dysfunctional Fronto-Temporal Memory Systems In Schizophrenia. |
Models For Studying Biological Mechanisms Implicated In Psychiatric DisordersAndres Buonanno, Chair And Peter Penzes, Co-chair1:00 pm: Andrés Buonanno, NIH Neuregulin-ErbB Signaling Modulates Neuronal Networks And Rodent Behaviors Associated With Psychiatric Disorders 1:30 pm: Peter Penzes, Northwestern Molecular Substrates Of Abnormal Dendritic Spine Plasticity In Schizophrenia 2:00 pm: Eleanor Simpson, Columbia Schizophrenia Endophenotypes In A Mouse Model Of Striatal Dopamine Dysfunction 2:30 pm: Tracey Petryshen, Harvard New Approaches To Animal Models In The Modern Psychiatric Genomics Era |
3:00 pm | Discussion | Discussion |
3:30 pm | Break | |
4:00 pm |
Transcriptome Regulation In Human Brain: Implications For Psychiatric Genetics And BeyondDaniel R. Weinberger., Chair And Bob Niculescu, Co-chair4:00 pm: Yuan Gao, Johns Hopkins Solving The RNA SEQ Riddle In Human Brain 4:30 pm: Jim Knowles, USC RNA Expression During Human Brain Development 5:00 pm: Andrew Jaffe, Lieber Institute Leveraging RNA-SEQ To Identify Molecular Mechanisms Of Risk From GWAS-positive Genomic Regions 5:30 pm: Daniel Weinberger, Lieber Institute RNA SEQ In Brain And The Identification Of Novel Therapeutic Targets In Psychiatry |
Synaptic And Circuit Mechanisms Underlying Neuropsychiatric DisordersRob Malenka, Chair And Lu Chen, Co-chair4:00 pm: Lu Chen, Stanford Homeostatic Synaptic Scaling And Fragile X Syndrome 4:30 pm: Stephen Shabel, Ucsd Chronic SSRI Treatment Enhances Co-release Of GABA From Glutamatergic Axons In The Lateral Habenula 5:00 pm: Jason Aoto, Stanford Neurexin-3 Alternative Splicing – Insights Into The Synaptic Function Of Neurexins 5:30 pm: Kimberly Thompson, Circuit Therapeutics Behavioral Conditioning By Optogenetic Recruitment Of Prefrontal Circuits |
6:00 pm | Discussion | Discussion |
Saturday, November 9th
Time | Pacific Room JK | |
---|---|---|
8:00 am | Plenary Session: William Byerey, Introduction: Louis Ptacek, UCSF: Clinical, Genetic And Molecular Characterization Of Circadian And Related Phenotypes | |
8:50 am | Break | |
Time | Pacific Room JK | Pacific Room M |
9:00 am |
Imaging Studies Of AutismSteve Dager, Chair And Natalia Kleinhan, Co-chair9:00 am: Jason Wolff, UNC-Chapel Charting The Early Neurobehavioral Development Of Autism 9:30 am: Natalia Kleinhan, University Of Washington Abnormal Brain Connectivity In Autism 10:00 am: Declan Murphy, Kings College London Using ‘Translational Neuroscience’ To Identify Novel Treatment Targets For Autism. A European Approach. 10:30 am: Steve Dager, University Of Washington Developmental Patterns Of Brain Chemical Changes In Autism |
Life In The Post-GWAS Era: Moving From Association To Gene FunctionCathy Barr, Chair And Jim Knowles, Co-chair9:00 am: Cathy Barr, University Of Toronto Decoding The Non-coding Genome: Functional Annotation Of Genetic Variation In Gene Regulatory Regions 9:30 am: Nancy Cox, University of Chicago Reverse Reverse Genetics 10:00 am: Marquis Vawter, University Of California, Irvine Next Generation Sequencing Of Transcriptome To Unravel Pathophysiology Of Schizophrenia 10:30 am: James Ellis, University Of Toronto Rett Syndrome IPS Cell Models Of MECP2 Isoform Function |
11:00 am | Discussion | Discussion |
11:20 am | Break | |
11:30 am – Concurrent Sessions With Lunch Provided |
Disturbances In Glutamate-GABA Interactions In Local Circuits: Implicaitons For Abnormal Functional Connectivity In SchizophreniaJohn Krystal, Chair And Kevin Spencer, Co-chair11:30 am: John Murray, Yale Computational Modeling Of The Impact Of NMDA Receptor Dysfunction Upon The Regulation Of Local Cortical Circuits And Cortical Information Processing 12:00 pm: Brendon O. Watson, NYU GABA Neuronal Heterogeneity: Differential Impact Of Pv And Sst Neuronal Dysfunction For Cortical And Hippocampal Excitability And Oscillatory Activity 12:30 pm: Alan Anticevic, Yale NMDA Receptor Antagonist Effects, Schizophrenia, And Cortical Functional Connectivity: Impact Of The Phase Of Schizophrenia Illness 1:00 pm: Kevin Spencer, Harvard Abnormalities In Gamma Oscillations In Schizophrenia: Signal-to-Noise Issues |
Genetics Of SchizophreniaAiden Corvin, Chair And Mick O’Donovan, Co-chair11:30 am: Aiden Corvin, Trinity College Update On Analyses From The PGC2 Schizophrenia GWAS Analyses 12:00 pm: Ole Andreassen, University Of Oslo Shared Gene Loci Between Schizophrenia And Comorbid Diseases Suggest Polygenic Pleiotropy 12:30 pm: Christian Marshall, University Of Toronto Meta-analysis Of CNVs From The PGC Schizophrenia Dataset 1:00 pm: Mick O’Donovan, Cardiff University Exome Sequencing Studies Of SZ Implicates Pathways Affecting Synaptic Plasticity |
1:30 pm | Discussion | Discussion |
1:50 pm | Break | |
2:00 pm |
Genetics Of Neurodevelopmental DisordersNancy Cox, Chair And Jeremiah Scharf, Co-chair2:00 pm: Jeremiah Scharf, Harvard Medical School Comparative Genomics Of Tourette Syndrome And Obsessive-Compulsive Disorder 2:30 pm: Tom Fernandez, Yale CNV Studies Of TS 3:00 pm: Lea Davis, University Of Chicago The Genetic Architecture Of Tourette Syndrome And Obsessive Compulsive Disorder 3:30 pm: Alysa Doyle, Harvard Medical School Translating Advances In Psychiatric Genetics To A Child Clinical Cohort |
Genetics Of Mood DisordersJohn Kelsoe, Chair And Seth Ament, Co-chair2:00 pm: Seth Ament, Institue Of System Biology Sequencing In BP Families Followup Studies 2:30 pm: John Kelsoe, UCSD Functional Variants Affecting Neurotrophin Signaling Are Associated With Bipolar Disorder 3:00 pm: Dick McCombie, Cold Spring Harbor Case Control And Family Based Studies Of Bipolar Disorder – How To Merge The Information 3:30 pm: Fernando Goes, Johns Hopkins Searching For Rare Genetic Variants In Bipolar Disorder Using Exome Sequencing |
4:00 pm | Discussion | Discussion |
4:20 pm | Break | |
4:30 pm |
Neurobiology Of AutismMike Gill, Chair And Louise Gallagher, Co-chair4:30 pm: Matt State, UCSF Autism Genomics 4:54 pm: Laurie Weiss, UCSF Autism And The Ras/MAPK Pathway 5:18 pm: Brent Bill, Semel Institute For Neuroscience And Human Behavior, University Of California Zebrafish: A Developing Tool For ASD Research. 5:42 pm: Sanbing Shen, School Of Medicine, National University Of Ireland Galway Involvement Of A Novel Kinase ULK4 In Neurodevelopmental Disorders In Mice And Humans 6:06 pm: Vinod Menon, Stanford University School Of Medicine Brain Structure And Connectivity In Autism |
Pathways In Bipolar DisordersChris Ross. Chair And Pamela Sklar, Co-chair4:30 pm: Pamela Sklar, Mt Sinai Bipolar Genetics / Functional Genomics 4:54 pm: Chris Ross, Johns Hopkins Ank-G/ CACNA1C Pathway 5:18 pm: Tracey Petryshen, Massachusetts General Hospital Ankyrin-G Mouse Model 5:42 pm: Peter Klein, University Of Pennsylvania WNT And GSK-3 Signaling 6:06 pm: Stephen J. Haggarty, Harvard Therapeutic Targets And Drug Development |
6:30 pm | Discussion | Discussion |
Sunday, November 10th
Time | Pacific Room JK | |
---|---|---|
8:00 am | Plenary Session: Pablo Gejman, Introduction: Thomas Lehner, NIMH: Opportunities And Challenges In Psychiatric Genetics: An NIMH Perspective | |
8:50 am | Break | |
Time | Pacific Room JK | Pacific Room M |
9:00 am |
Biomarkers For Mood DisordersJair Soares, Chair And Trevor Young, Co-chair9:00 am: Ana Andreazza, University Of Toronto The Interface Between Peripheral And Central Markers Of Oxidative Stress In Psychiatry 9:30 am: Chris W. Turck, Max Planck Institute Of Psychiatry Antidepressant Drug Response: From Pathways To Biosignatures 10:00 am: Chadi Abdallah, Yale In Vivo In Humans: Interrogation Of The Glutamatergic Synapse 10:30 am: Mark A. Frye, Mayo Clinic Antidepressant Induced Mania: Phenotype And Genotype Evaluation |
Genetics Of Drug AbuseJoel Gelernter, Chair And Caryn Lerman, Co-chair9:00 am: Can Yang, Yale Exploring The Genetic Architecture Of Alcohol Dependence In African-americans Via Analysis Of A Genomewide Set Of Common Variants 9:30 am: Caryn Lerman, University Of Pennsylvania Comt Variation, Working Memory, And Nicotine Addiction Treatment 10:00 am: Andrew Bergen, Sri International Pharmacogenetics Of Smoking Cessation: Pharmacodynamics And Pharmacokinetic Candidate Gene Studies Motivated By Genome-wide Association And Linkage 10:30 am: Joel Gelernter, Yale Findings From Alcohol And Nicotine GWAS Studies |
11:00 am | Discussion | Discussion |
11:30 am | Lunch | |
1:00 pm |
Biomarkers For SchizophreniaAkira Sawa, Chair And Ty Cannon, Co-chair1:00 pm: Ty Cannon, Yale Biomarkers Of Risk And Progression To Full Psychosis In Individuals At Clinical High Risk 1:30 pm: Thomas Sedlak, Johns Hopkins Oxidative Stress And Inflammatory Pathways At The Crossroads Of Psychosis Risk Factors And Pathogenesis 2:00 pm: Akira Sawa, Johns Hopkins Biomarkers For Cognitive Deficits And Cortical Structural Changes: From Genetic Clue To Translational Application 2:30 pm: Alexander Herman, UCSF Plasticity In Cortical High-gamma Oscillations Mediates Behavioral Improvement From Targeted Computer Training In Schizophrenia |
Neural Stem Cell ResearchJohn Kelsoe, Chair And Kristen Brennand, Co-chair1:00 pm: Jun Yao, Tsinghua University Evaluating Bipolar Patient Neurons Using iPSC Technology 1:30 pm: Sue O’shea, University Of Michigan Induced Pluripotent Stem Cell Models Of Bipolar Disorder 2:00 pm: Kristin Brennand, Mt. Sinai Modeling Predisposition To Schizophrenia Using Induced Pluripotent Stem Cells 2:30 pm: Guo-li Ming, Johns Hopkins Function Of Risk Genes For Mental Disorders In Neural Development |
3:00 pm | Discussion | Discussion |
3:30 pm | Break | |
4:00 pm |
Infections, Inflammation, And Psychiatric DisordersBob Yolken, Chair And Faith Dickerson, Co-chair4:00pm: Bob Yolken, Johns Hopkins School Of Medicine The Other Human Genome-the Role Of The Microbiome In Human Psychiatric Disorders 4:20 pm: Emily Severance, Johns Hopkins School Of Medicine Intestinal Inflammation And Complement Activation In Psychiatric Disorders 4:40 pm: Vish Nimgaonkar, University Of Pittsburgh School Of Medicine Gene-Environmental Interactions In Human Psychiatric Disorders 5:00 pm: Michael Benros, Universities Of Aarhus And Copenhagen Infections And Autoimmune Diseases As Risk Factors For Schizophrenia And Mood Disorders 5:20 pm: Faith Dickerson, Sheppard Pratt Hospital Infectious And Immunologic Markers And Cognitive Functioning In Individuals With And Without Psychiatric Disorders 5:40 pm: Sarven Sabunciyan, Johns Hopkins School Of Medicine DNA Methylation And Inflammation In Mania |
PharmacogeneticsAnil Malhotra, Chair And Jim Kennedy, Co-chair4:00 pm: Akira Sawa, Johns Hopkins Gene Expression Changes In Response To Antipsychotic Drug Treatment 4:24 pm: John Kelsoe, UCSD Pharmacogenetics Of Lithium Response 4:48 pm: Anil Mahotra, Hofstra School Of Medicine Pharmacogenetics Of Antipsychotic Drug-induced Side Effects 5:12 pm: Jim Kennedy, University Of Toronto Pharmacogenetics In Schizophrenia 5:36 pm: Martin Schalling, Karolinska Institutet Long-term Lithium Treatment In Bipolar Disorder Is Associated With Longer Telomeres |
6:00 pm | Discussion | Discussion |
The 2013 Molecular Psychiatry meeting is supported in part by generous contributions from the Department of Psychiatry at UCSD, the University of Southern California and Wiley.